Toxoplasmosis Ocular Tratamiento Pdf Free
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Antetoxoplasma therapy should be initiated with pyrimethamine plus sulfadiazine or, if this is contraindicated, with ofloxacin or clindamycin plus pyrimethamine and sulfadiazine. In most patients, the therapy regimen should contain one of the following drugs: pyrimethamine plus clindamycin, clindamycin plus sulfadiazine, or pyrimethamine plus sulfadiazine.
Supplicant's optic neuropathy is uncommon in young and middle-aged patients with chronic toxoplasmosis, but it is common among older patients with chronic disease. Supplicant's fellow eye can also be affected.
Pyrimethamine and pyrimethamine plus sulfadiazine used in the treatment of toxoplasmosis in pregnancy in immunocompetent women does not have teratogenic or embryotoxic effects. However, congenital brain malformations, especially microcephaly, have been described, but the data showing this are limited and conflicting.
Laboratory findings were similar for different treatment groups, but the duration of the follow-up was not long enough to draw conclusions about long-term outcomes. The vision of the right eye improved significantly in all patients, but there was no significant difference in vision between the groups. Visual acuity at least improved in all patients.
The evolution of retinal lesions is variable. The course of retinochoroiditis is more severe and prolonged in patients with CT than in controls; retinochoroiditis may be more severe if the toxoplasmosis is active and if there is a delay in starting treatment. After initiation of therapy, the lesions may resolve or persist. The current evidence suggests that preventive therapy is not necessary after an adequately treated infection. d2c66b5586
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